Optimize the preclinical MRI protocols to improve their robustness to respiratory motion-induced corruption, distortion and blur. Assess the repeatability of quantitative imaging markers in GEM model of pancreatic cancer.
Design and perform preclinical studies that match an ongoing clinical trial that evaluate the stroma-directed agent on pancreatic cancer microenvironment. Perform co-clinical imaging studies in human and GEM model.
Build a web resource to demonstrate the effective optimizations of the motion-robust methods, share protocols, tools and SOPs. Enhance the accessibility, clarity and sustainability of the webpage.
Preclinical / Clinical Trials & Quantitative Imaging Methods
View full profile >Quantitative Imaging Methods
View full profile >Preclinical / Clinical Trials
View full profile >Web Resources
View full profile >The NCI Co-Clinical Imaging Research Resource Program (CIRP) promotes development of quantitative imaging resources for therapeutic or prevention co-clinical trials that study both patients and human-in-mouse models. The resources will encourage a consensus on optimizing quantitative imaging methods and develop standard operating procedures for co-clinical applications
View site >The NCI CIRP Wiki will be used as the network workspace for intra-network communications & scientific discussions and serves as the network homepage for publishing news/events and announcing activities externally.
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